Research Publications
2026
Gao, Han and Tennakoon, Rasangi and Araújo. A disease-causing isoleucyl-tRNA synthetase variant leads to altered protein complex formation and cellular stress response.. J Biol Chem, 302, 111196 (2026). DOI
Moore, Nathan and Taylor-Edmonds, Liz and Zollbrecht, Nicole and Yeung, Kirsten and Sun, Jianxian and Legaspi-Annett, Kevin and Vanyo, Katie and Barreto Bossoni, Gabriela and Chen, Tianyi and Manek, Vishal and Mackey, Erin and Peng, Hui and Andrews, Susan and Hofmann, Ron. Disinfection byproducts and cellular toxicity from UV/chlorine advanced oxidation for potable reuse and drinking water treatment compared to chlorination and UV/hydrogen peroxide.. Sci Total Environ, 1011, 181151 (2026). DOI
Liu, Jiabao and Li, Hao and Tian, Yintai and Guo, Miao and Sahin, Cigdem and Kamata, Shotaro and Honda, Akihiro and Campbell, Jhenielle and Shi, Jin and Yurtal, Emine Dide and Yang, Diwen and Jachimowicz, Matthew and Hu, Shian and Gong, Yufeng and Navarre, William and Ishii, Isao and Cummins, Carolyn L and Peng, Hui* and Wang, Shengpeng* and Wang, Xiaojuan* and Mani, Sridhar* and Krause, Henry M*. Microbial 10-oxostearic acid protects mice against colitis via the nuclear receptor PPARα.. Nat Microbiol (2026). DOI
Yeung, Kirsten and Zhao, Xinda and Hall, David Ross and Han, Jiajun and Peng, Hui. Revisiting Quinone-Induced Oxidative Stress via Structure-Related Protein Alkylation.. Environ Sci Technol (2026). DOI
2025
Wang, Xiaojuan and Zhang, Guohui and Bian, Zhiwei and Chow, Vimanda and Grimaldi, Marina and Carivenc, Coralie and Sirounian, Savannah and Li, Hao and Sladekova, Lucia and Mott, Stefano and Luperi, Yulia and Gong, Yufeng and Costello, Cait and Li, Linhao and Jachimowicz, Matthew and Guo, Miao and Hu, Shian and Wilson, Derek and Balaguer, Patrick and Bourguet, William and Mani, Sridhar and Bonati, Laura and Peng, Hui and March, John and Wang, Hongbing and Wang, Shengpeng and Krause, Henry M and Liu, Jiabao. An abundant ginger compound furanodienone alleviates gut inflammation via the xenobiotic nuclear receptor PXR in mice.. Nat Commun, 16, 1280 (2025). DOI
Fan, XR and Li, XM and Li, T and Shao, B and Niu, S and Fan, WH and Wang, Q and Zhong, L and Wang, XR and Wang, ZW and Ma, FJ and Zheng GM and Peng, H and Chen, LL and Dong, ZM. Binding of per- and polyfluoroalkyl substances with liver and serum proteins in rats: implications for physiologically based pharmacokinetic modelling. Environment International, 201 (2025).
Das, Sourav and Peng, Hui and Wiseman, Clare L S. Characterizing the metal(loid) contribution to the oxidative potential of thoracic-sized road dust particles.. Environ Pollut, 383, 126785 (2025). DOI
Miller, Jolie and Han, Jiajun and Yang, Diwen and Diamond, Miriam L and Liu, Runzeng and Peng, Hui. Chemical proteomics reveals human liver fatty acid binding protein as a predominant and selective target of triphenyl phosphate.. Environ Sci Process Impacts (2025). DOI
Wang, Xiaoyun and Sun, Jianxian and Ahmad, Shabbir and Yang, Diwen and Li, Fengling and Chan, U Hang and Zeng, Hong and Simoben, Conrad V and Green, Stuart R and Silva, Madhushika and Houliston, Scott and Dong, Aiping and Bolotokova, Albina and Gibson, Elisa and Kutera, Maria and Ghiabi, Pegah and Kondratov, Ivan and Matviyuk, Tetiana and Chuprina, Alexander and Mavridi, Danai and Lenz, Christopher and Joerger, Andreas C and Brown, Benjamin D and Heath, Richard B and Yue, Wyatt W and Robbie, Lucy K and Beyett, Tyler S and M\. Enantioselective protein affinity selection mass spectrometry (E-ASMS).. Nat Commun (2025). DOI
Li, R and Barrett, H and Nair, P and Wang, MH and Tomlin, H and Atkinson, JB and Krogh, E and Xie, LN and Peng, H. Enantioselectivity in Metabolism and Toxicity of 6PPD-Quinone in Salmonids. Environmental Science and Technology, 59 (2025).
Wang, Xinke and Fahy, William D and Xie, Linna and Peng, Hui and Abbatt, Jonathan P D. Fast autoxidation of unsaturated lipid films on indoor surfaces.. Nat Commun, 16, 1557 (2025). DOI
Seabrook, Katryna J and Winn, Louise M and Brinkmann, Markus and Adams, Julie E and Canete, Ashley and Xie, Linna and Peng, Hui and Robinson, Stacey A and Orihel, Diane M. First assessment of the ecotoxicological effects of the tire antioxidant 6PPD on early life stages of the popular sport fish species, the largemouth bass (Micropterus nigricans).. Environ Toxicol Chem (2025). DOI
Yeung, Kirsten and Xie, Linna and Nair, Pranav and Peng, Hui. Haloacetonitriles Induce Structure-Related Cellular Toxicity Through Distinct Proteome Thiol Reaction Mechanisms.. ACS Environ Au, 5, 101-113 (2025). DOI
Wang, Yutong and Yang, Diwen and Fahy, William and Rivellini, Laura-Helena and Peng, Hui and Abbatt, Jonathan. Increased UV\textendash. Environmental Science and Technology Letters (2025).
Peng, Hui and Kotelnikov, Sergei and Egbert, Megan E and Ofaim, Shany and Stevens, Grant C and Phanse, Sadhna and Saccon, Tatiana and Ignatov, Mikhail and Dutta, Shubham and Istace, Zoe and Moutaoufik, Mohamed Taha and Aoki, Hiroyuki and Kewalramani, Neal and Sun, Jianxian and Gong, Yufeng and Padhorny, Dzmitry and Poda, Gennady and Alekseenko, Andrey and Porter, Kathryn A and Jones, George and Rodionova, Irina and Guo, Hongbo and Pogoutse, Oxana and Datta, Suprama and Saier, Milton and Crovella, Mark and Vajda, Sandor and Moreno-Hagelsieb, Gabriel and Parkinson, John and Segre, Daniel and Babu, Mohan and Kozakov, Dima and Emili, Andrew. Ligand interaction landscape of transcription factors and essential enzymes in E.~coli.. Cell (2025). DOI
Hou, Xingwang and Gauthier, Jeremy R and Nair, Pranav and Fahy, William D and Peng, Hui and Mabury, Scott A. New Sources of Very Persistent and Very Mobile (vPvM) Substances: A Case Study of the Fluorinated Herbicide Pyroxasulfone.. Environ Sci Technol (2025). DOI
Liu, Min and Xia, Chunjie and Peng, Hui and Zvereva, Elizaveta and Burns, Darcy C and Fontaine, Justine and Blum, Arlene and Spentzos, Ariana Z and Wang, Zhanyun and Peaslee, Graham F and Sauv\'e. Nonpolymeric Per- and Polyfluoroalkyl Substances (PFAS) and Side-Chain Fluorinated Polymers in Canadian Building Products.. Environ Sci Technol (2025). DOI
Edwards, Aled M and Owen, Dafydd R. Protein-ligand data at scale to support machine learning.. Nature Reviews Chemistry (2025). DOI
Ng, Desmond and Chen, Yuhao and Lei, Ying Duan and Chen, Wanzhen and Peng, Hui and Gourlie, Sarra and Wania, Frank. Quantifying the Effect of Dietary Microplastics on the Potential for Biological Uptake of Environmental Contaminants and Polymer Additives.. Environ Sci Technol (2025). DOI
Li, Zhuoyuan and Xie, Linna and Nair, Pranav and Yeung, Kirsten and Meek, Oliver and Tao, Juan and Hiki, Kyoshiro and Hao, Chunyan and Peng, Hui. A Rapid Testing Kit for 6PPD Screening in Rubber Products.. Anal Chem (2025). DOI
Chen, Wanzhen and Miller, Jolie M and Burns, Darcy C and Almuhtaram, Husein and Andrews, Robert C and Peng, Hui. Semiquantitative Nontargeted Screening of Organophosphorus Plastic Additives in Consumer Products Using P NMR.. Environ Sci Technol (2025). DOI
Nair, Pranav and Barrett, Holly and Tanoto, Kaylin and Xie, Linna and Sun, Jianxian and Yang, Diwen and Yao, Han and Song, Datong and Peng, Hui. Structure and Toxicity Characterization of Alkyl Hydroxylated Metabolites of 6PPD-Q.. Environ Sci Technol (2025). DOI
Nair, Pranav and Sun, Jianxian and Xie, Linna and Kennedy, Lisa and Kozakiewicz, Derek and Kleywegt, Sonya M and Hao, Chunyan and Byun, Hannah and Barrett, Holly and Baker, Joshua and Monaghan, Joseph and Krogh, Erik T and Song, Datong and Peng, Hui. Synthesis and Toxicity Evaluation of -Phenylenediamine-Quinones.. Environ Sci Technol (2025). DOI
Rodgers, TFM and Drew, S and Brown, T and Hiki, K and Hiroshi, Y and King, M and Kolodziej, EP and Krogh, ET and Mclntyre, JK and Miller, K and Peng, H and Tomlin, H and Wang, Y and Scholes, RC. Turning the Corner on Hazardous Tire Compounds: A Management Framework for Tire Additive Pollution. Environmental Science and Technology Letters (2025).
Chen, Wanzhen and Almuhtaram, Husein and Andrews, Robert and Peng, Hui. Unanticipated Thio-Oxidation of Organophosphite Chemical Additives in PVC Microplastics Following In Situ Weathering. ACS ES\&T Water (2025).
2024
Xie, Linna and Yuan, Lai and Sun, Jianxian and Yang, Miqing and Khan, Ismail and Lopez, Joselyn and Gong, Yufeng and Nair, Pranav and Hao, Chunyan and Helm, Paul and Barrett, Holly and Edwards, Elizabeth and Peng, Hui. Compound Class-Specific Temporal Trends (2021\textendash. ACS ES\&T Water (2024).
Liu, Jiabao and Malekoltojari, Aniaz and Asokakumar, Anjana and Chow, Vimanda and Li, Linhao and Li, Hao and Grimaldi, Marina and Dang, Nathanlown and Campbell, Jhenielle and Barrett, Holly and Sun, Jianxian and Navarre, William and Wilson, Derek and Wang, Hongbing and Mani, Sridhar and Balaguer, Patrick and Anakk, Sayeepriyadarshini and Peng, Hui* and Krause, Henry*. Diindoles produced from commensal microbiota metabolites function as endogenous CAR/Nr1i3 ligands. Nature Communications (2024).
Barrett, Holly and Sun, Jianxian and Chen, Yuhao and Yang, Diwen and Verreault, Jonathan and Houde, Magali and Wania, Frank and Peng, Hui. Emerging investigator series: nontargeted screening of aryl hydrocarbon receptor agonists in endangered beluga whales from the St. Lawrence Estuary: beyond legacy contaminants.. Environ Sci Process Impacts, 26, 1451-1464 (2024). DOI
Fahy, William D and Gong, Yufeng and Wang, Shenghong and Zhang, Zhizhen and Li, Li and Peng, Hui and Abbatt, Jonathan P D. Hydroxyl radical oxidation of chemical contaminants on indoor surfaces and dust.. Proc Natl Acad Sci U S A, 121, e2414762121 (2024). DOI
Goitom, Eyerusalem and Ariano, Sarah and Gilbride, Kim and Yang, Minqing Ivy and Edwards, Elizabeth A and Peng, Hui and Dannah, Nora and Farahbakhsh, Farnaz and Hataley, Eden and Sarvi, Hooman and Sun, Jianxian and Waseem, Hassan and Oswald, Claire. Identification of environmental and methodological factors driving variability of Pepper Mild Mottle Virus (PMMoV) across three wastewater treatment plants in the City of Toronto.. Sci Total Environ, 932, 172917 (2024). DOI
Gong, Yufeng and Sun, Jianxian and Wang, Xiaoyun and Barrett, Holly and Peng, Hui. Identification of Hydrocarbon Sulfonates as Previously Overlooked Transthyretin Ligands in the Environment.. Environ Sci Technol (2024). DOI
Liu-Kang, Carolyn and Sokolova, Anna and Gong, Yufeng and Fahy, William D and Peng, Hui and Abbatt, Jonathan PD. Light Exposure of Wood Smoke Aerosol: Connecting Optical Properties, Oxidation, Radical Formation, and Chemical Composition. ACS ES\&T Air, 1 (2024).
Wang, Chao and Gu, Wen and Zhang, Shaoping and Li, Li and Kong, Jian and Zhi, Hong and Liu, Juan and Wang, Mengmeng and Miao, Ke and Li, Qi and Yu, Jie and Wang, Runming and He, Runming and Zhang, Shuyi and Deng, Fuchang and Duan, Shuling and Zhang, Qiannan and Liu, Zhenming and Yang, Hui and Jia, Xudong and Peng, Hui and Tang, Song. Multigenerational effects of disperse blue 79 at environmentally relevant concentrations on zebrafish (Danio rerio) fecundity: An integrated approach.. J Hazard Mater, 478, 135442 (2024). DOI
Yu, Jie and Gong, Yufeng and Nair, Pranav and Liggio, John and Peng, Hui* and Abbatt, Jonathan P D*. Multiphase Ozonolysis of Bisphenol A: Chemical Transformations on Surfaces in the Environment.. Environ Sci Technol (2024). DOI
Xie, Linna and Yu, Jie and Nair, Pranav and Sun, Jianxian and Barrett, Holly and Meek, Oliver and Qian, Xing and Yang, Diwen and Kennedy, Lisa and Kozakiewicz, Derek and Hao, Chunyan and Hansen, John D and Greer, Justin B and Abbatt, Jonathan P D and Peng, Hui. Structurally Selective Ozonolysis of -Phenylenediamines and Toxicity in Coho Salmon and Rainbow Trout.. Environ Sci Technol (2024). DOI
Sun, Jianxian and Yang, Minqing Ivy and Peng, Jiaxi and Khan, Ismail and Lopez, Jhoselyn Jaramillo and Chan, Ronny and Edwards, Elizabeth A and Peng, Hui. Underestimation of SARS-CoV-2 in wastewater due to single or double mutations in the N1 qPCR probe binding region.. Water Res X, 22, 100221 (2024). DOI
Zvekic, Misha and Barrett, Holly and Diamente, Peter and Peng, Hui and Krogh, Erik T. Unique hepatic maternal transfer pattern of trace metals and perfluoroalkyl substances (PFAS) in a bluntnose sixgill shark (Hexanchus griseus).. Chemosphere, 359, 142315 (2024). DOI
2023
Peng, JX and Chan, C and Zhang, SL and Sklavounos, AA and Olson, ME and Scott, EY and Hu, YC and Rajesh, V and LI, BB and Chamberlain, MD and Zhang, S and Peng, H and Wheeler, AR. All-in-one digital microfluidics pipeline for proteomic sample preparation and analysis. Chemical Science (2023).
Gong, YF and Yang, DW and Barrett, H and Yang, DW and Peng, H. Building the Environmental Chemical-Protein Interaction Network (eCPIN): An Exposome-Wide Strategy for Bioactive Chemical Contaminant Identification. Environmental Science and Technology (2023).
Simond, Antoine \'E. Declining concentrations of chlorinated paraffins in endangered St. Lawrence Estuary belugas (Delphinapterus leucas): Response to regulations or a change in diet?. Sci Total Environ, 161488 (2023). DOI
Gong, Yufeng and Yang, Diwen and Liu, Jiabao and Barrett, Holly and Sun, Jianxian and Peng, Hui. Disclosing Environmental Ligands of L-FABP and PPARγ: Should We Re-evaluate the Chemical Safety of Hydrocarbon Surfactants?. Environ Sci Technol (2023). DOI
Wang, Shunyao and Gallimore, Peter J and Liu-Kang, Carolyn and Yeung, Kirsten and Campbell, Steven J and Utinger, Battist and Liu, Tengyu and Peng, Hui and Kalberer, Markus and Chan, Arthur W H and Abbatt, Jonathan P D. Dynamic Wood Smoke Aerosol Toxicity during Oxidative Atmospheric Aging.. Environ Sci Technol (2023). DOI
Zhang, CZ and Liu, SH and Feng, HD and Barrett, H and Karunaratne, SHP and Zhang, Y and Yang, M. Effects of Triclosan on the Development of Antimicrobial Resistance in the Environment: A Review. Current Pollution Report (2023).
Wu, MH and Chen, WZ and Peng, H and Almuhtaram H and Andrews RC. Leaching of dibutyltin dichloride from virgin polyvinyl chloride (PVC) pipe material. ACS ES\&T Water (2023).
Deng, Fuchang and Qin, Guangqiu and Chen, Yuanyuan and Zhang, Xu and Zhu, Mu and Hou, Min and Yao, Qiao and Gu, Wen and Wang, Chao and Yang, Hui and Jia, Xudong and Wu, Chongming and Peng, Hui and Du, Huamao and Tang, Song. Multi-omics reveals 2-bromo-4,6-dinitroaniline (BDNA)-induced hepatotoxicity and the role of the gut-liver axis in rats.. J Hazard Mater, 457, 131760 (2023). DOI
Schwartz-Narbonne, Heather and Xia, CJ and Shalin, A and Whitehead, HD and Yang, DW and Peaslee, Graham F and Wang, ZY and Wu, Y and Peng, H and Blum, A and Venier, M and Diamond, ML. Per- and Polyfluoroalkyl Substances in Canadian Fast Food Packaging. Environ. Sci. Technol. Lett (2023).
Cao, YQ and Chen, YY and Miao, K and Zhang, SY and Deng, FC and Zhu, M and Wang, C and Gu, W and Huang, YX and Shao, ZJ and Dong, XY and Gong YF and Peng, H and Yang, H and Wan, Y and Jia, XD and Tang, S. PPARg as a potential target for adipogenesis induced by fine particulate matter in 3T3-L1 preadipocytes. Environmental Science and Technology (2023).
Zhang, Zhizhen and Li, Li and Peng, Hui and Wania, Frank. Prioritizing molecular formulae identified by non-target analysis through high-throughput modelling: application to identify compounds with high human accumulation potential from house dust.. Environ Sci Process Impacts (2023). DOI
Hall, David Ross and Gauthier, Jeremy and Peng, Hui. Querying the In Vitro Proteome Cysteine Reactivity of 8:2 Fluorotelomer Acrylate.. Environ Sci Technol (2023). DOI
Kutarna, S and Chen, WZ and Xiong, Y and Liu, RZ and Gong, YF and Peng, H. Screening of Indoor Transformation Products of Organophosphates and Organophosphites with an in Silico Spectral Database. ACS measurement Science Au (invited article) (2023).
Yeung, KY and Moore, N and Sun, JX and Edmonds, LT and Andrews, S and Hofmann, R and Peng, H. Thiol Reactome: A Nontargeted Strategy to Precisely Identify Thiol Reactive Drinking Water Disinfection Byproducts. Environmental Science and Technology (2023).
Kutarna, S and Du, X and Diamond, ML and Blum, A and Peng, H. Widespread Presence of Chlorinated Paraffins in Consumer Products. Environmental Science: Processes \& Impacts (2023).
2022
Sun, Jianxian and Xu, Chenke and Peng, Hui and Wan, Yi and Luo, Kai and Barrett, Holly and Hu, Jianying. Behaviors and trophodynamics of o,p\textquoteright. Sci Total Environ, 153447 (2022). DOI
Wu, Xiaoqin* and Nguyen, Helen and Kim, Damian and Peng, Hui*. Chronic toxicity of PFAS-free AFFF alternatives in terrestrial plant Brassica rapa.. Sci Total Environ, 158100 (2022). DOI
Arts, E and Brown, S and Bulir, D and Charles, TC and DeGroot, CT and Delatolla, R and Desaulniers, JP and Edwards, EA and Fuzzen, M and Gilbride, K and Gilchrist, J and Goodridge, L and Graber, T and Habash, M and Juni, P and Kirkwood, A and Knockleby, J and Kyle, C and Landgraff, C and Mangat, C and Manuel, DG and McKay, RM and Mejia, E and Mloszewska, A and Ormeci, B and Oswald, C and Payne, SJ and Peng, H and Peterson, S and Poon, A and Servos, MR and Simmons, D and Sun, JX and Yang MQ and Ybazeta, G. Community Surveillance of Omicron in Ontario: Wastewater-based Epidemiology Comes of Age. Research Square (2022).
Chen, Wanzhen and Gong, Yufeng and Michael, McKie and Husein, Almuhtaram and Sun, Jianxian and Barrett, Holly and Yang, Diwen and Wu, Menghong and Andrews, Robert and Peng, Hui. Defining the Chemical Additives Driving In Vitro Toxicities of Plastics. Environ. Sci. Technol. (2022).
Peng, JX and Sun, JX and Yang, MQ and Gibson, R and Arts, E and Olabode, AS and Poon, AF and Wang, XY and Wheeler, AR and Edwards, E and Peng, H. Early Warning Measurement of SARS-CoV-2 Variants of Concern in Wastewaters by Mass Spectrometry. Environ. Sci. Technol. Lett (2022).
Ma, Chunmeng and Peng, Hui and Chen, Hongrui and Shang, Wei and Zheng, Xingcan and Yang, Min and Zhang, Yu. Long-term trends of fluorotelomer alcohols in a wastewater treatment plant impacted by textile manufacturing industry.. Chemosphere, 134442 (2022). DOI
Joudan, Shira and Barrett, Holly and Silva, Amila O De and Solla, Shane R and Peng, Hui and Deon, Jessica C. Measuring Perfluoroalkyl Acid Contamination at a Local Hot Spot: An Authentic Field-Based Laboratory Experience in a Senior Analytical Environmental Chemistry Course. Journal of Chemical Education (2022).
Liu, JB and Sahin, C and Ahmad, S and Magomedova, L and Zhang, MH and Jia, ZP and Metherel, AH and Orellana, A and Poda, G and Bazinet, RP and Attisano, L and Cummins, CL and Peng, H* and Krause, H*. The omega-3 hydroxy fatty acid 7(S)-HDHA is a high-affinity PPARα ligand that regulates brain neuronal morphology. Science Signaling (2022).
Xia, Chunjie and Diamond, Miriam L and Peaslee, Graham F and Peng, Hui and Blum, Arlene and Wang, Zhanyun and Shalin, Anna and Whitehead, Heather D and Green, Megan and Schwartz-Narbonne, Heather and Yang, Diwen and Venier, Marta. Per- and Polyfluoroalkyl Substances in North American School Uniforms.. Environ Sci Technol (2022). DOI
Pileggi, V and Shurgold, J and Sun, JX and Yang, MQ and Edwards, E and Peng, H and Tehrani A and Gilbride, KA and Oswald CJ and Wijayasri, S and AI-Bargash, D and Stuart, R and Khansari, Z and Raby, M and Thomas, J and Fletcher, T and Simon, A. Quantitative Trend Analysis of SARS-CoV-2 RNA in Municipal Wastewater Exemplified with Sewershed-Specific COVID-19 Clinical Case Counts. ACS ES\&T Water, 2 (2022).
Barrett, Holly and Sun, Jianxian and Gong, Yufeng and Yang, Paul and Hao, Chunyan and Verreault, Jonathan and Zhang, Yu and Peng, Hui. Triclosan is the Predominant Antibacterial Compound in Ontario Sewage Sludge. Environmental Science and Technology, 56 (2022).
D\textquoteright. Wastewater to clinical case (WC) ratio of COVID-19 identifies insufficient clinical testing, onset of new variants of concern and population immunity in urban communities.. Sci Total Environ, 158547 (2022). DOI
Yang, Diwen and Liu, Qifan and Wang, Sizhi and Bozorg, Martin and Liu, Jiabao and Nair, Pranav and Balaguer, Patrick and Song, Datong and Krause, Henry and Ouazia, Boualem and Abbatt, Jonathan and Peng, Hui. Widespread formation of toxic nitrated-bisphenols indoors by heterogeneous reactions with HONO. Science Advances (2022).
2021
Sun, Jianxian and Barrett, Holly and Hall, David and Kutarna, Steven and Wu, Xiaoqin and Wang, Yan and Peng, Hui. Ecological Role of 6OH-BDE47: Is It a Chemical Offence Molecule Mediated by Enoyl-ACP Reductases?. Environ. Sci. Technol. (2021).
Steven Kutarna and Song Tang and Xiaojian Hu and Hui Peng. Enhanced Nontarget Screening Algorithm Reveals Highly Abundant Chlorinated Azo Dye Compounds in House Dust. Environ. Sci. Technol., 55 (2021).
Han, JJ and Fu, J and Sun, JX and Hall, DR and Yang, DW and Blatz, D and Houck, KA and Ng, CA and Doering, JA and LaLone, CA and Peng, H. Quantitative Chemical Proteomics Reveals Interspecies Variations on Binding Schemes of L-FABP with Perfluorooctanesulfonate. Environ. Sci. Technol., 55 (2021).
Han, JJ and Gu, W and Barrett, H and Yang, DW and Tang, S and Sun, JX and Liu, JB and Krause, HM and Houck, KA and Peng, H. A Roadmap to the Structure-Related Metabolism Pathways of Per- and Polyfluoroalkyl Substances in the Early Life Stages of Zebrafish (Danio rerio). Environ. Health. Perspect., 129 (2021).
Barrett, Holly and Du, Xuan and Houde, Magali and Lair, St\'e. Suspect and Nontarget Screening Revealed Class-Specific Temporal Trends (2000-2017) of Poly- and Perfluoroalkyl Substances in St. Lawrence Beluga Whales.. Environ Sci Technol (2021). DOI
2020
Hall, David Ross and Peng, Hui. Characterizing physical protein targets of chemical contaminants with chemical proteomics: Is it time to fill a crucial environmental toxicology knowledge gap?. Comp Biochem Physiol Part D Genomics Proteomics (invited perspective), 34, 100655 (2020). DOI
Brinkmann, Markus and Alharbi, Hattan and Fuchylo, Ulyana and Wiseman, Steve and Morandi, Garrett and Peng, Hui and Giesy, John P and Jones, Paul D and Hecker, Markus. Mechanisms of pH-Dependent Uptake of Ionizable Organic Chemicals by Fish from Oil Sands Process-Affected Water (OSPW).. Environ Sci Technol, 54, 9547-9555 (2020). DOI
Hall, DR and Yeung, K and Peng, H. Monohaloacetic Acids and Monohaloacetamides Attack Distinct Cellular Proteome Thiols. Environ. Sci. Technol., 54 (2020).
Yang, DW and Han, JJ and Hall, DR and Sun, JX and Fu, J and Kutarna, S and Houck, KA and LaLone, CA and Doering, JA and Ng, CA and Peng, H. Nontarget Screening of Per- and Polyfluoroalkyl Substances Binding to Human Liver Fatty Acid Binding Protein. Environ. Sci. Technol., 54 (2020).
Han, Jiajun and Wang, Shunyao and Yeung, Kirsten and Yang, Diwen and Gu, Wen and Ma, Zhiyuan and Sun, Jianxian and Wang, Xiaomin and Chow, Chung-Wai and Chan, Arthur W H and Peng, Hui. Proteome-wide effects of naphthalene-derived secondary organic aerosol in BEAS-2B cells are caused by short-lived unsaturated carbonyls.. Proc Natl Acad Sci U S A (2020). DOI
Han, Jiajun and Yang, Diwen and Hall, David Ross and Liu, Jiabao and Sun, Jianxian and Gu, Wen and Tang, Song and Alharbi, Hattan A and Jones, Paul D and Krause, Henry M and Peng, Hui. Toxicokinetics of Brominated Azo Dyes in the Early Life Stages of Zebrafish () Is Prone to Aromatic Substituent Changes.. Environ Sci Technol, 54, 4421-4431 (2020). DOI
2019
Dhungana, Birendra and Peng, Hui and Kutarna, Steven and Umbuzeiro, Gisela and Shrestha, Sujan and Liu, Jing and Jones, Paul D and Subedi, Bikram and Giesy, John P and Cobb, George P. Abundances and concentrations of brominated azo dyes detected in indoor dust.. Environ Pollut, 252, 784-793 (2019). DOI
Xiaohui Zhang and Song Tang and Mao Wang and Weimin Sun and Yuwei Xie and Hui Peng and Aimin Zhong and Hongling Liu and Xiaowei Zhang and Hongxia Yu and John P. Giesy and Markus Hecker. Acid mine drainage affects the diversity and metal resistance gene profile of sediment bacterial community along a river. Chemosphere, 217, 790-199 (2019). DOI
Zhang, Shiyi and Kang, Qiyue and Peng, Hui and Ding, Mengyu and Zhao, Fanrong and Zhou, Yuyin and Dong, Zhaomin and Zhang, Haifeng and Yang, Min and Tao, Shu and Hu, Jianying. Relationship between perfluorooctanoate and perfluorooctane sulfonate blood concentrations in the general population and routine drinking water exposure.. Environ Int, 126, 54-60 (2019). DOI
Hu, Wenxin and Jia, Yingting and Kang, Qiyue and Peng, Hui and Ma, Haojia and Zhang, Shiyi and Hiromori, Youhei and Kimura, Tomoki and Nakanishi, Tsuyoshi and Zheng, Lemin and Qiu, Yifu and Zhang, Zhaobin and Wan, Yi and Hu, Jianying. Screening of House Dust from Chinese Homes for Chemicals with Liver X Receptors Binding Activities and Characterization of Atherosclerotic Activity Using an Macrophage Cell Line and Mice.. Environ Health Perspect, 127, 117003 (2019). DOI
Xie, Xianyi and Jin, Yaru and Ma, Zhiyuan and Tang, Song and Peng, Hui and Giesy, John P and Liu, Hongling. Underlying mechanisms of reproductive toxicity caused by multigenerational exposure of 2, bromo-4, 6-dinitroaniline (BDNA) to Zebrafish (Danio rerio) at environmental relevant levels.. Aquat Toxicol, 216, 105285 (2019). DOI
2018
Codling, Garry and Hosseini, Soheil and Corcoran, Margaret B and Bonina, Solidea and Lin, Tian and Li, An and Sturchio, Neil C and Rockne, Karl J and Ji, Kyunghee and Peng, Hui and Giesy, John P. Current and historical concentrations of poly and perfluorinated compounds in sediments of the northern Great Lakes - Superior, Huron, and Michigan.. Environ Pollut, 236, 373-381 (2018). DOI
Ma, Zhiyuan and Peng, Hui and Jin, Yaru and Zhang, Xianming and Xie, Xianyi and Jian, Kang and Liu, Hongling and Su, Guanyong and Tang, Song and Yu, Hongxia. Multigenerational Effects and Demographic Responses of Zebrafish ( Danio rerio) Exposed to Organo-Bromine Compounds.. Environ Sci Technol, 52, 8764-8773 (2018). DOI
Apenova, Nancy and Peng, Hui and Hecker, Markus and Brinkmann, Markus. A rapid and sensitive fluorometric method for determination of aldehyde oxidase activity.. Toxicol Appl Pharmacol, 341, 30-37 (2018). DOI
Zhang, Shiyi and Peng, Hui and Mu, Di and Zhao, Haoqi and Hu, Jianying. Simultaneous determination of (N-ethyl perfluorooctanesulfonamido ethanol)-based phosphate diester and triester and their biotransformation to perfluorooctanesulfonate in freshwater sediments.. Environ Pollut, 234, 821-829 (2018). DOI
Gole, Vitthal L and Sierra-Alvarez, Reyes and Peng, Hui and Giesy, John P and Deymier, Pierre and Keswani, Manish. Sono-chemical treatment of per- and poly-fluoroalkyl compounds in aqueous film-forming foams by use of a large-scale multi-transducer dual-frequency based acoustic reactor.. Ultrason Sonochem, 45, 213-222 (2018). DOI
Codling, Garry and Sturchio, Neil C and Rockne, Karl J and Li, An and Peng, H and Tse, Timothy J and Jones, Paul D and Giesy, John P. Spatial and temporal trends in poly- and per-fluorinated compounds in the Laurentian Great Lakes Erie, Ontario and St. Clair.. Environ Pollut, 237, 396-405 (2018). DOI
2017
Chen, Hongrui and Peng, Hui and Yang, Min and Hu, Jianying and Zhang, Yu. Detection, Occurrence, and Fate of Fluorotelomer Alcohols in Municipal Wastewater Treatment Plants.. Environ Sci Technol, 51, 8953-8961 (2017). DOI
Peng, Hui and Sun, Jianxian and Saunders, David M V and Codling, Garry and Wiseman, Steve and Jones, Paul D and Giesy, John P. Hydroxylated 2-Ethylhexyl tetrabromobenzoate isomers in house dust and their agonistic potencies with several nuclear receptors.. Environ Pollut, 227, 578-586 (2017). DOI
Sun, Jianxian and Peng, Hui* and Alharbi, Hattan A and Jones, Paul D and Giesy, John P and Wiseman, Steve B. Identification of Chemicals that Cause Oxidative Stress in Oil Sands Process-Affected Water.. Environ Sci Technol, 51, 8773-8781 (2017). DOI
Guo, Hongbo and Peng, Hui and Emili, Andrew. Mass spectrometry methods to study protein-metabolite interactions.. Expert Opin Drug Discov, 12, 1271-1280 (2017). DOI
Peng, Hui and Saunders, David M V and Jones, Paul D and Giesy, John P. Response to Comment on. Environ Sci Technol, 51, 3591-3592 (2017). DOI
2016
Sun, Jianxian and Tang, Song and Peng, Hui* and Saunders, David M V and Doering, Jon A and Hecker, Markus and Jones, Paul D and Giesy, John P and Wiseman, Steve. Combined Transcriptomic and Proteomic Approach to Identify Toxicity Pathways in Early Life Stages of Japanese Medaka (Oryzias latipes) Exposed to 1,2,5,6-Tetrabromocyclooctane (TBCO).. Environ Sci Technol, 50, 7781-90 (2016). DOI
Doering, Jon A and Tang, Song and Peng, Hui and Eisner, Bryanna K and Sun, Jianxian and Giesy, John P and Wiseman, Steve and Hecker, Markus. High Conservation in Transcriptomic and Proteomic Response of White Sturgeon to Equipotent Concentrations of 2,3,7,8-TCDD, PCB 77, and Benzo[a]pyrene.. Environ Sci Technol, 50, 4826-35 (2016). DOI
Peng, Hui and Saunders, David M V and Sun, Jianxian and Jones, Paul D and Wong, Chris K C and Liu, Hongling and Giesy, John P. Mutagenic Azo Dyes, Rather Than Flame Retardants, Are the Predominant Brominated Compounds in House Dust.. Environ Sci Technol, 50, 12669-12677 (2016). DOI
Peng, Hui and Sun, Jianxian and Alharbi, Hattan A and Jones, Paul D and Giesy, John P and Wiseman, Steve. Peroxisome Proliferator-Activated Receptor γ is a Sensitive Target for Oil Sands Process-Affected Water: Effects on Adipogenesis and Identification of Ligands.. Environ Sci Technol, 50, 7816-24 (2016). DOI
Sun, Jianxian and Wang, Chen and Peng, Hui and Zheng, Guomao and Zhang, Shiyi and Hu, Jianying. p,p\textquoteright. Environ Sci Technol, 50, 462-9 (2016). DOI
Rodriguez-Freire, Lucia and Abad-Fern\'a. Sonochemical degradation of perfluorinated chemicals in aqueous film-forming foams.. J Hazard Mater, 317, 275-283 (2016). DOI
Yuan, Guanxiang and Peng, Hui and Huang, Chong and Hu, Jianying. Ubiquitous Occurrence of Fluorotelomer Alcohols in Eco-Friendly Paper-Made Food-Contact Materials and Their Implication for Human Exposure.. Environ Sci Technol, 50, 942-50 (2016). DOI
Peng, Hui and Guo, Hongbo and Pogoutse, Oxana and Wan, Cuihong and Hu, Lucas Z and Ni, Zuyao and Emili, Andrew. An Unbiased Chemical Proteomics Method Identifies FabI as the Primary Target of 6-OH-BDE-47.. Environ Sci Technol, 50, 11329-11336 (2016). DOI
Peng, Hui and Chen, Chunli and Cantin, Jenna and Saunders, David M V and Sun, Jianxian and Tang, Song and Codling, Garry and Hecker, Markus and Wiseman, Steve and Jones, Paul D and Li, An and Rockne, Karl J and Sturchio, Neil C and Giesy, John P. Untargeted Screening and Distribution of Organo-Bromine Compounds in Sediments of Lake Michigan.. Environ Sci Technol, 50, 321-30 (2016). DOI
Peng, Hui and Chen, Chunli and Cantin, Jenna and Saunders, David M V and Sun, Jianxian and Tang, Song and Codling, Garry and Hecker, Markus and Wiseman, Steve and Jones, Paul D and Li, An and Rockne, Karl J and Sturchio, Neil C and Cai, Minghong and Giesy, John P. Untargeted Screening and Distribution of Organo-Iodine Compounds in Sediments from Lake Michigan and the Arctic Ocean.. Environ Sci Technol, 50, 10097-105 (2016). DOI
2015
Peng, Hui and Saunders, David M V and Sun, Jianxian and Codling, Garry and Wiseman, Steve and Jones, Paul D and Giesy, John P. Detection, identification, and quantification of hydroxylated bis(2-ethylhexyl)-tetrabromophthalate isomers in house dust.. Environ Sci Technol, 49, 2999-3006 (2015). DOI
Zhang, Zhong and Peng, Hui and Wan, Yi and Hu, Jianying. Isomer-specific trophic transfer of perfluorocarboxylic acids in the marine food web of Liaodong Bay, North China.. Environ Sci Technol, 49, 1453-61 (2015). DOI
Mu, Di and Gao, Fumei and Fan, Zhanlan and Shen, Huan and Peng, Hui and Hu, Jianying. Levels of Phthalate Metabolites in Urine of Pregnant Women and Risk of Clinical Pregnancy Loss.. Environ Sci Technol, 49, 10651-7 (2015). DOI
Jianxian, Sun and Hui, Peng and Jianying, Hu. Temporal trends of polychlorinated biphenyls, polybrominated diphenyl ethers, and perfluorinated compounds in Chinese sturgeon (Acipenser sinensis) eggs (1984-2008).. Environ Sci Technol, 49, 1621-30 (2015). DOI
Peng, Hui and Chen, Chunli and Saunders, David M V and Sun, Jianxian and Tang, Song and Codling, Garry and Hecker, Markus and Wiseman, Steve and Jones, Paul D and Li, An and Rockne, Karl J and Giesy, John P. Untargeted Identification of Organo-Bromine Compounds in Lake Sediments by Ultrahigh-Resolution Mass Spectrometry with the Data-Independent Precursor Isolation and Characteristic Fragment Method.. Anal Chem, 87, 10237-46 (2015). DOI
2014
Peng, Hui and Zhang, Shiyi and Sun, Jianxian and Zhang, Zhong and Giesy, John P and Hu, Jianying. Isomer-specific accumulation of perfluorooctanesulfonate from (N-ethyl perfluorooctanesulfonamido)ethanol-based phosphate diester in Japanese Medaka (Oryzias latipes).. Environ Sci Technol, 48, 1058-66 (2014). DOI
Zhang, Qinqin and Jia, Ai and Wan, Yi and Liu, Hong and Wang, Kunping and Peng, Hui and Dong, Zhaomin and Hu, Jianying. Occurrences of three classes of antibiotics in a natural river basin: association with antibiotic-resistant Escherichia coli.. Environ Sci Technol, 48, 14317-25 (2014). DOI
Peng, Hui and Wan, Yi and Zhang, Kun and Sun, Jianxian and Hu, Jianying. Trophic transfer of dechloranes in the marine food web of Liaodong Bay, north China.. Environ Sci Technol, 48, 5458-66 (2014). DOI
2013
Peng, Hui and Hu, Kejun and Zhao, Fanrong and Hu, Jianying. Derivatization method for sensitive determination of fluorotelomer alcohols in sediment by liquid chromatography-electrospray tandem mass spectrometry.. J Chromatogr A, 1288, 48-53 (2013). DOI
Tong, Xunliang and Peng, Hui and Liu, Donghui and Ji, Liang and Niu, Chenguang and Ren, Jun and Pan, Bing and Hu, Jianying and Zheng, Lemin and Huang, Yining. High-density lipoprotein of patients with type 2 diabetes mellitus upregulates cyclooxgenase-2 expression and prostacyclin I-2 release in endothelial cells: relationship with HDL-associated sphingosine-1-phosphate.. Cardiovasc Diabetol, 12, 27 (2013). DOI
2012
Sun, Jianxian and Hu, Jianying and Peng, Hui and Shi, Jiachen and Dong, Zhaomin. Molecular and physiological characterization of fluoroquinolone resistance in relation to uropathogenicity among Escherichia coli isolates isolated from Wenyu River, China.. Chemosphere, 87, 37-42 (2012). DOI
Ding, Huanhuan and Peng, Hui and Yang, Min and Hu, Jianying. Simultaneous determination of mono- and disubstituted polyfluoroalkyl phosphates in drinking water by liquid chromatography-electrospray tandem mass spectrometry.. J Chromatogr A, 1227, 245-52 (2012). DOI
Peng, Hui and Zhang, Kun and Wan, Yi and Hu, Jianying. Tissue distribution, maternal transfer, and age-related accumulation of dechloranes in Chinese sturgeon.. Environ Sci Technol, 46, 9907-13 (2012). DOI
2011
Jia, Ai and Hu, Jianying and Wu, Xiaoqin and Peng, Hui and Wu, Shimin and Dong, Zhaomin. Occurrence and source apportionment of sulfonamides and their metabolites in Liaodong Bay and the adjacent Liao River basin, North China.. Environ Toxicol Chem, 30, 1252-60 (2011). DOI
2010
Wu, Xiaoqin and Hu, Jianying and Jia, Ai and Peng, Hui and Wu, Shimin and Dong, Zhaomin. Determination and occurrence of retinoic acids and their 4-oxo metabolites in Liaodong Bay, China, and its adjacent rivers.. Environ Toxicol Chem, 29, 2491-7 (2010). DOI
Peng, Hui and Wei, Qiwei and Wan, Yi and Giesy, John P and Li, Luoxin and Hu, Jianying. Tissue distribution and maternal transfer of poly- and perfluorinated compounds in Chinese sturgeon (Acipenser sinensis): implications for reproductive risk.. Environ Sci Technol, 44, 1868-74 (2010). DOI
2009
Hu, Jianying and Zhang, Zhaobin and Wei, Qiwei and Zhen, Huajun and Zhao, Yanbin and Peng, Hui and Wan, Yi and Giesy, John P and Li, Luoxin and Zhang, Bo. Malformations of the endangered Chinese sturgeon, Acipenser sinensis, and its causal agent.. Proc Natl Acad Sci U S A, 106, 9339-44 (2009). DOI